Metastatic Brain Tumors in Adults

A metastatic brain tumor is cancer that has spread to the brain from another part of the body. Any type of tumor can spread to the brain, but the most common ones include cancers of the lung, breast, gastrointestinal tract, and kidney, as well as melanoma. Our doctors collaborate to create a personalized treatment plan for you, which may include a combination of treatments such as surgery, Gamma Knife® radiosurgery, chemotherapy, and radiation therapy.

Clinical Trials and Research Studies

Phase 1/2

An Open-Label Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination with REGN2810 in Subjects with Newly-Diagnosed Glioblastoma (GBM)

Phase 2

APEC1621C: NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Phase 2 Subprotocol of Tazemetostat in Patients with Tumors Harboring Alterations in EZH2 or Members of the SWI/SNF Complex

Phase 2/3

A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma P2/3 Randomized Study of Toca 511 & Toca FC Versus SOC in Subjects Undergoing Surgery for Recurrent GBM/AA (Toca5)

Phase 1

ONC201 in Newly Diagnosed Diffuse Intrinsic Pontine Glioma and Recurrent/Refractory Pediatric H3 K27M Gliomas